Endocrine Abstracts

Purpose: We sought to determine if in the group of patients who underwent gynecologic abdominal interventions diabetes was an independent risk factor of perioperative complications.Material and methods: The study group included 62 women from both the diabetic and the control group who underwent elective gynecologic laparotomies such as hysterectomy or adnexectomy. The patients from diabetic group were pair-matched with patients without diabetes based on ...

Introduction: Increased production of vasopressin plays a key role in the development of fluid retention and hyponatremia in patients with decompensated heart failure. Antidiuretic hormone deficiency in the course of diabetes insipidus leads to the loss of water, dehydration and hypernatremia. The aim of the study was to present difficulties in successful treatment of hyponatremia in a patient with cardiomyopathy and heart failure, receiving desmopressin because of postoperati...

Introduction: The enlarged pituitary gland of pregnancy is susceptible to any compromise to its blood supply. Sheehan’s syndrome (SS) occurs as a result of post-partum pituitary infarction or haemorrhage and usually leads to hypopituitarism. It can be fatal but clinical manifestations may change from one patient to another and symptoms may not occur for many years.Methods: We analysed retrospectively five cases of women with SS aged 26&#150...

Introduction: Bilateral adrenalectomy (BA) is rarely applied as a therapeutic procedure. It serves as a life-saving treatment in patients with persistent Cushing’s disease after an ineffective pituitary surgery or in ectopic ACTH production. Other indications for BA are: bilateral adrenocortical adenomas, congenital adrenal hyperplasia and bilateral phaeochromocytoma in patients with hereditary paraganglioma-phaeochromocytoma (PPS/PGL) syndromes. It is also a procedure of...

Introduction: Hyponatremia occurs in 33–69% of women with postpartum pituitary necrosis. The aim of the study was to present a patient in whom recurrent hyponatremia was one of the dominant symptoms of postpartum anterior pituitary hormones deficiency.A case report: 55-year-old woman with a diagnosis of Sheehan syndrome established 19 years after the last labor complicated by massive bleeding due to uterine atonia. The first symptoms of pituitary in...

Cyclophosphamide is an alkylating agent used in the treatment of malignant and autoimmune diseases. Severe hyponatraemia is a serious electrolyte disorder with life threatening neurological sequelae. We report a case of recurrent severe, symptomatic hyponatraemia that developed in a 61 year old female with systemic vasculitis and Sjogrens syndrome following low-dose cyclophosphamide.Case report: A 61 year old lady, with ANA positive systemic vasculitis p...

Introduction: Alopecia areata affects 0.1–0.2% of population. It’s pathogenesis has not yet been discovered, but genetic, autoimmune, vascular, psychogenic or neurological factors are being considered. It can occur in any age, but appears most commonly in late childhood, teenage or early adulthood. Alopecia areata commonly coexists with other diseases such as asthma, allergic rhinitis, atopic dermatitis, thyroid diseases and autoimmune diseases such as thyroiditis an...

A 67-year-old male with PTC (pT3N0) underwent a total thyroidectomy in February 2004. Subsequently he was treated with I-131 and radiotherapy (RT). Combined therapy did not normalize the serum thyroglobulin (TG). Because of elevated TG and persistent I-131 uptake in thyroid bed the patient received a total activity of 21275 MBq of I-131 in 4 years. The treatment was stopped in March 2007 due to a lack of I-131 uptake in the last post-therapeutic whole body scan (WBS) with stil...

Introduction: Multiple endocrine neoplasia type 2A (MEN2A) is a multi-glandular autosomal dominant genetic disorder which, most typically, includes medullary carcinoma of the thyroid, pheochromocytoma and primary hyperparathyroidism. The authors present a case study of a young man in whom cardiogenic shock was the first manifestation of pheochromocytoma and MEN2A.Case report: A 30-year-old man without a past history of hypertension or any other chronic m...

Introduction: Serotonin producing neuroendocrine tumors are usually well differentiated, small lesions localised in the small intestine. Visualisation of the primary tumor might be difficult due to its small size.Case report: A 52 years old man presented with diarrhoea and flushes. Ultrasound examination and computed tomography of the abdomen revealed numerous lesions in the liver. Gastroscopy, colonoscopy and magnetic resonance imaging did not reveal th...